Category Archives: Genetic Therapy

Tumor's Genetic Identity Not Revealed By Single Biopsy

Featured Article Academic Journal Main Category: Cancer / Oncology Also Included In: Genetics;Urology / Nephrology Article Date: 08 Mar 2012 – 2:00 PST email to a friend printer friendly opinions Current Article Ratings: 4 (3 votes) 3 (3 votes) Professor Peter Johnson, chief clinician at Cancer Research UK said in a statement that the study highlights “important differences that exist within tumours and suggest a way to improve the success rate of personalised cancer medicines”. The lead author of the study is Professor Charles Swanton, who works at Cancer Research UK’s London Research Institute and the UCL Cancer Institute. He and his colleagues analyzed the genetic variation among different regions of the same cancer tumor, using samples donated by patients with advanced kidney cancer Continue reading

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Genetic manipulation boosts growth of brain cells linked to learning, enhances antidepressants

Public release date: 8-Mar-2012 [ | E-mail | Share ] Contact: Deborah Wormser deborah.wormser@utsouthwestern.edu 214-648-3404 UT Southwestern Medical Center DALLAS — UT Southwestern Medical Center investigators have identified a genetic manipulation that increases the development of neurons in the brain during aging and enhances the effect of antidepressant drugs. Continue reading

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Genetic Makeup of Tumors More Complex Than Thought

New Research Shows Personalized Treatment for Cancer Not So Simple WebMD Health News March 8, 2012 — A small study that shows a surprising complexity of genetic changes within a single tumor has far-reaching implications for the march toward personalized cancer therapy, according to researchers. A single biopsy from a tumor might not be sufficient to give a full picture of its genetic landscape, a team from the United Kingdom reports Continue reading

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Genetic manipulation boosts growth of brain cells linked to learning, enhances effects of antidepressants

ScienceDaily (Mar. 8, 2012) UT Southwestern Medical Center investigators have identified a genetic manipulation that increases the development of neurons in the brain during aging and enhances the effect of antidepressant drugs. Continue reading

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Cancer chimeras complicate therapy

NO WONDER cancer is such a challenge to treat: a genetic analysis of advanced kidney cancer has shown that mutations can vary across the same tumour. This finding dashes hopes of tailoring treatment for an individual based on the mutations in a single biopsy. Charles Swanton at Cancer Research UK in London and colleagues analysed kidney tumours from four people and found that around two-thirds of genetic mutations in the same tumour differed from one biopsy to the next. Continue reading

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Abbott and Merck Collaborate to Develop Companion Diagnostic Test for Investigational Cancer Therapy

ABBOTT PARK, Ill., March 6, 2012 /PRNewswire/ — Abbott (NYSE: ABT – News) announced today that it will collaborate with Merck to evaluate the use of a FISH (fluorescence in situ hybridization)-based companion diagnostic test to aid in the development of a Merck investigational cancer therapy. Continue reading

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Transgenomic’s Proprietary Clopidogrel (Plavix®) Response Panel Includes Both Genetic Markers Demonstrated to Be …

OMAHA, Neb.–(BUSINESS WIRE)– Transgenomic, Inc. (OTCBB: TBIO.OB – News) today announced the publication of a new study by researchers at Vanderbilt University that further validates the role of both genes found in the Companys PGxPredict:CLOPIDOGREL (Plavix) Panel, a comprehensive test to predict a patients response to clopidogrel (Plavix). Continue reading

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Lotus Tissue Repair Announces Support of First International Patient Registry for Epidermolysis Bullosa (EB) and …

CAMBRIDGE, Mass.–(BUSINESS WIRE)– Lotus Tissue Repair, Inc., a biotechnology company developing the first and only protein replacement therapy for the treatment of the rare genetic disorder dystrophic epidermolysis bullosa (DEB), today announced that it is providing grants to support the development and maintenance of the first international EB patient-reported registry, EBCare.org. The registry was launched today by the DEB Research Association (DEBRA) International and DEBRA of America in conjunction with Rare Disease Day, as Lotus Tissue Repair participated in a Rare Disease Day event hosted by the Massachusetts Biotechnology Council at the Massachusetts State House. Continue reading

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Ultragenyx Granted Orphan Drug Designation for UX003 for the Treatment of Mucopolysaccharidosis Type 7 (MPS 7)

NOVATO, Calif., Feb. 28, 2012 /PRNewswire/ — Ultragenyx Pharmaceutical Inc., a biotechnology company focused on developing treatments for rare and ultra-rare genetic disorders, today announced that the FDA Office of Orphan Products Development has granted orphan drug designation for UX003 for the treatment of MPS 7. MPS 7 is an extremely rare autosomal recessive lysosomal storage disorder characterized by a deficiency of the lysosomal enzyme Beta-glucuronidase, required for the degradation of the glycosaminoglycans dermatan sulfate (DS) and heparan sulfate (HS). Continue reading

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bluebird bio to Present at Cowen and Company 32nd Annual Health Care Conference

CAMBRIDGE, Mass.–(BUSINESS WIRE)– bluebird bio, a leader in the development of innovative gene therapies for severe genetic disorders, announced today that Nick Leschly, chief executive officer, is scheduled to present at the Cowenand Company32nd AnnualHealth Care Conference on Tuesday, March 6, 2012 at 8:30a.m. Continue reading

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Genetic Technologies Provides Update on U.S. and Australian Gene Patenting Litigation, Case Law and Legislation

MELBOURNE, AUSTRALIA–(Marketwire -02/29/12)- Genetic Technologies Limited (ASX: GTG.AX – News) (NASDAQ: GENE – News) wishes to update the Market on its position with respect to U.S. and Australian legislation, litigation and case law regarding gene patenting. Continue reading

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Story on human genetic origins is one of EurekAlert!s most-visited releases in 2011

Public release date: 27-Feb-2012 [ | E-mail | Share ] Contact: Jennifer Santisi jsantisi@aaas.org 202-326-6213 American Association for the Advancement of Science A striking discovery in the study of human genetics was the focus of the most-visited press release posted on EurekAlert! in 2011. Researchers found that part of the non-African human X chromosome came from Neanderthals, confirming that they interbred with early human populations Continue reading

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Nephrologists Agree That There is a High Unmet Need for an Effective Treatment to Slow Renal Disease Progression in …

EXTON, Penn.–(BUSINESS WIRE)– In a recent survey of 100 U.S. nephrologists, it was reported that there is an extremely high need for new therapies targeted at Polycystic Kidney Disease (PKD), a genetic disorder characterized by the growth of numerous cysts in the kidneys Continue reading

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Genetic Technologies Announces Financial Results for Half-Year Ended 31 December 2011

MELBOURNE, AUSTRALIA–(Marketwire -02/27/12)- Genetic Technologies Limited (ASX: GTG.AX – News) (NASDAQ: GENE – News) BREVAGen launch off to strong start with sales trends accelerating into early 2012 Reimbursement economics improving as Company executes contracts with leading U.S. PPOs Genetic Technologies Limited (ASX: GTG.AX – News) (NASDAQ: GENE – News) today announced financial results for the first half of the Company’s fiscal year ending 30 June 2012. The Company reported a total comprehensive loss of $3.3 million, which compares to a gain of $4.2 million in the prior year period Continue reading

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This year's wish

Grace C. Mae shouldn't be alive. Doctors told her mother that, because of a rare genetic disease, she wouldn't survive the pregnancy. Continue reading

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Genetic basis of age-related macular degeneration identified

Home > News > health-news Washington, Feb 24 : Scientists have identified genes whose expression levels can identify people with age-related macular degeneration (AMD) as well as tell apart its subtypes. AMD is one of the leading causes of blindness worldwide, especially in developed countries, and there is currently no known treatment or cure or for the vast majority of AMD patients Continue reading

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Cancer cure hopes as genetic code hereditary breast disease is mapped for first time

By John Hutchinson Last updated at 8:51 PM on 23rd February 2012 Discovery: Scientists from around Europe have joined forces to discover more about the genetics of breast cancer (Posed by models) The genetic code of the most common type of hereditary breast cancer has been mapped for the first time, raising hopes for better diagnosis and treatment for the killer disease, scientists said. Researchers say they have 'fully sequenced' the DNA of two breast cancers caused by a faulty BRCA1 gene, which is responsible for aggressive and highly drug-resistant tumours Continue reading

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Specially-bred mice help target an annual outbreak: the flu

Public release date: 21-Feb-2012 [ | E-mail | Share ] Contact: Jim Newman newmanj@ohsu.edu 503-494-8231 Oregon Health & Science University PORTLAND, Ore ? As part of a national collaboration, Oregon Health & Science University researchers are studying specially bred mice that are more like humans than ever before when it comes to genetic variation. Continue reading

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Genetic Technologies Successfully Concludes Second Patent Infringement Suit in USA

MELBOURNE, AUSTRALIA–(Marketwire -02/21/12)- Genetic Technologies Limited (ASX: GTG.AX – News) (NASDAQ: GENE – News), today announced the successful conclusion of the second assertion suit having now executed a Settlement with a group of companies associated with Sonic Healthcare Limited (“Sonic Affiliates”). Continue reading

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DNA Vaccine Therapy in the Treatment of Cancer HIV Infection and All Genetic Diseases – Video


06-10-2011 07:43 YES LADIES AND GENTLEMEN THE CURE FOR ALL DISEASE. The FDA and The American Government has been suppressing the Cure For Cancer and Aids for more than 20 years … The United States wouldn’t be having Health Care Budget Problems if the Cures were released. Continue reading

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